I am at work and suffering at the hands of my antivirus scanner. Every time I launch a process it runs through its entire database of virus sigs and does a compare. This is frustratingly slow, so I have disabled it. (Gasp!)
This led me to a little internal rant - not the "antivirus is completely useless" rant that you see often on the web, rather the "antivirus is not effective prevention, rather it's a cleanup tool".
In the good ol' days, if a new virus appeared on the scene, it took weeks, if not months to make its way around the world, which meant that unless you were particularly unlucky, your antivirus defs would be up to date well before you encountered the virus, and the antivirus program would block it. Neat.
Now that the Internet is commonplace, viruses spread much faster than researchers at antivirus companies can create signatures.
Antivirus is essentially a huge blacklist. The problem with a blacklist is it can only block items it knows are problematic. What we really need is a whitelist - only run programs approved for use.
Now if you get infected, and you update your signatures, antivirus software is very good at cleaning up the virus (if not so good at actually repairing data), but they all advertise antivirus as a preventative measure.
The only time antivirus is a preventative measure is if you're in a very security unaware company where the same virus keeps breaking out again and again over the network. In this case, I'd advise you (if allowed) to firewall yourself off and only turn off the firewall when you need to access a network resource. At the very least, disable your administrative shares permanently.
-- Edit-- Just had to add this: The human immune system is amazing. It is a blacklist and a whitelist at the same time. Any unrecognized substances / cells that arrive in the body get attacked, and added to the blacklist for faster recognition and response in future. If only A/V software could do this! (obviously not to programs you were trying to install) ;-)
Disclaimer: Batteries not included. Barbie and Ken sold separately. Only effective in conjunction with a kilojoule-controlled diet.